Teste pentru detectia fungica specifica a antigenului Cryptococcus neoformans
Testul Dynamiker Cryptococcus neoformans Antigen Assay se bazeazape motoda tehnologica ELISA. Se utilizeaza pentru detectarea cantitativa a antigenului Cryptococcus neoformans glicuronoxilomanan (GXM) in serul uman sau lichidul cefalorahidian (CSF), oferind o referinta de diagnostic pentru infectia cu Cryptococcus neoformans.
Kitul este destinat numai pentru uz profesional.
Advantage
- Quantitative Detection;
- High Throughput;
- High Sensitivity;
- High Accuracy;
- Strong Anti-interference capability.
Features
- Forma de prezentare: Ser;
- Contine: 96 teste /kit;
- Detection Range 3.2-100μg/L;
- Percent Recovery 90-115%;
- Intra-assay CV ≤10%;
- Inter-assay CV ≤15%;
- Kit-ul poate fi depozitat dupa deschidere timp de 4 saptamani in sacul sigilat cu desicant la 2-8 ℃.
High-Risk Population
- HIV-infected patients;
- Organ transplant recipients;
- Patients receiving high-dose corticosteroid therapy;
- Patients receiving monoclonal antibodies (such as alemtuzumab, infliximab) therapy;
- Patients receiving other immunosuppressive therapies;
- Immunocompromised patients.
ELISA Method Has Much Fewer Confounding Factors thanLatex Agglutination
Latex Agglutination
- Factors for False Positivity;
- Serum containing rheumatoid factor;
- Specimens containing agar coagulant, hydroxyethyl starch;
- Serum trivalent Fe content exceeds 200mg/dl;
- Other microbial infections, such as Trichosporon sp.;
- Non-specific aggregation due to HIV infection;
- Inappropriate use of cleaning agents and testing agents, such as test slide;
- Treatment using pronase;
- Factors for False Negativity;
- In early stage of infection, GXM concentration is too low;
- Serum containing immune complexes;
- GXM antigen concentration is too high, resulting in postzone phenomenon;
- There is too little amount of fungal capsule, leading to low antigen secretion.
ELISA Method
- Other microbial infections, such as Trichosporon sp.;
- In early stage of infection, GXM concentration is too low;
- Serum containing immune complexes;
- There is too little amount of fungal capsule, leading to low antigen secretion.
Producator:
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Catalogul de produse Dynamiker